Endothelial Cells
Endothelial cell adhesion is the first step in a number of processes in human health and disease. In normal functioning of the immune system, white blood cells are recruited through the vascular endothelium to the underlying tissue to perform tasks related to inflammation and injury. In metastatic disease, tumor cells can invade tissues using similar mechanisms of transmigration as immune cells. One of the first steps in either process is cell adhesion to the endothelial cells lining the blood vessels.
The BioFlux System provides numerous advantages for assays requiring endothelial cells:
- Control shear flow during and after cell monolayer growth phase
- Pre-condition endothelial cells using shear flow or chemical agents
- Run up to 96 experiments at a time
- Lower media requirements due to low-volume microfluidic format
- Image cells directly in situ using high resolution microscopy
More information can be found in our Cellular Biology Application Notes.