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Product Information (8 items)
BioFlux Grant and Publication Kit
Contains useful figures, product photos, well plate diagrams, and written descriptions for the BioFlux System. Appropriate for new grant applications, scientific publications, and budget justifications.
Zip Archive, 33.7 MBytes, posted on Monday, August 02, 2010 at 12:32 PM
BioFlux Ordering Information
Adobe PDF, 22 KBytes, posted on Friday, January 08, 2010 at 4:15 PM
BioFlux Product Brochure
Adobe PDF, 1.7 MBytes, posted on Monday, August 24, 2009 at 2:22 PM
High Shear BioFlux Plate
Data sheet for High Shear BioFlux Plate. Designed to reach higher shear rates for vascular, platelet, thrombosis, and adhesion assays.
Adobe PDF, 444 KBytes, posted on Monday, July 13, 2009 at 1:37 PM
BioFlux 1000 Product Data Sheet
Contains a product overview and description along with key performance specifications.
Adobe PDF, 2.9 MBytes, posted on Monday, January 05, 2009 at 12:36 PM
BioFlux 200 Product Tutorial
An illustrated overview of BioFlux principals, components and applications.
Adobe PDF, 1.7 MBytes, posted on Saturday, November 29, 2008 at 11:16 PM
BioFlux Technology White Paper
Provides a more detailed description of BioFlux technology and principles of operation.
Adobe PDF, 3.2 MBytes, posted on Tuesday, November 25, 2008 at 9:27 AM
BioFlux 200 Product Data Sheet
Contains a product overview and description along with key performance specifications.
Adobe PDF, 276 KBytes, posted on Thursday, November 20, 2008 at 9:20 AM
Publications and Posters (23 items)
New device for high-throughput viability screening of flow biofilms (Stanford University - Matin Lab)
Appl Environ Microbiol. 2010 Jul;76(13):4136-42. Epub 2010 Apr 30. PMID: 20435763 [PubMed - in process]
Adobe PDF, 25 KBytes, posted on Friday, July 09, 2010 at 1:23 PM
Cancer Cell Invasion Poster Presentation
Poster presentation from AACR 2010
Adobe PDF, 1.1 MBytes, posted on Thursday, April 22, 2010 at 10:48 AM
Angiogenesis Poster Presentation
Poster presentation from SBS 2010. Covers angiogenesis and cancer cell invasion applications.
Adobe PDF, 1.1 MBytes, posted on Monday, April 19, 2010 at 9:29 AM
Shear-Enhanced Oral Microbial Adhesion (NIH - Palmer Lab)
Publication in J. of Applied and Environmental Microbiology from researchers at the NIH.
Adobe PDF, 24 KBytes, posted on Wednesday, January 13, 2010 at 11:35 AM
ASCB 2009 Poster - Angiongenesis and Cell Invasion
We demonstrate a microfluidic based method to follow angiogenesis or cell invasion in real time. The method enables acquisition of high content data by microscopy using microfluidic flow cells which are optimized for imaging.
Adobe PDF, 1.3 MBytes, posted on Tuesday, January 05, 2010 at 8:42 AM
Platelet adhesion and aggregation under flow using microfluidic flow cells
Journal of Visualized Experiments (Oct 2009)
Adobe PDF, 24 KBytes, posted on Tuesday, December 29, 2009 at 4:11 PM
Wound Healing Assays in Well Plate–Coupled Microfluidic Devices with Controlled Parallel Flow (JALA - Conant)
Journal of the Association for Laboratory Automation (Feb 2010)
Adobe PDF, 56 KBytes, posted on Tuesday, December 29, 2009 at 4:08 PM
Well Plate-Coupled Microfluidic Devices Designed for Facile Image-Based Cell Adhesion and Transmigration Assays (JBS - Conant)
Journal of Biomolecular Sciences - Dec 2009
Adobe PDF, 24 KBytes, posted on Tuesday, December 29, 2009 at 3:55 PM
THE INHIBITION OF TROPHOBLAST APOPTOSIS (St Georges Univ of London - James)
JL James, GStJ Whitley, JE Cartwright. St George's, University of London. Poster presentation from the International Society for the Study of Hypertension in Pregnancy.
Adobe PDF, 132 KBytes, posted on Thursday, October 01, 2009 at 10:56 AM
How It Works Article - Lab Manager
Article published in Lab Manager Magazine describing utility of BioFlux system for solving critical problems in life science research and drug discovery.
Adobe PDF, 92 KBytes, posted on Monday, August 24, 2009 at 8:59 AM
A Microfluidic System Designed to Observe Platelet Behavior under Controlled Shear in Real Time (ISTH 2009)
Poster presentation covering thrombosis and platelet adhesion applications.
Adobe PDF, 950 KBytes, posted on Monday, July 27, 2009 at 11:13 AM
Differentiation of Rat Mesenchymal Stem Cells Under Shear Stress (Millipore Cellutions)
Stem cell research has the potential to produce novel treatments for previously incurable diseases and injuries. For studies of stem cell differentiation, scientists have traditionally used biochemical stimulation. However, shear stress can also be used. Here we demonstrate the differentiation of rat mesenchymal stem cells into von Willebrand factor (vWF)-expressing endothelial cells as a result of shear stress.
Adobe PDF, 740 KBytes, posted on Tuesday, July 21, 2009 at 9:11 AM
Shear Flow Bibliography
A list of rlevant articles from the literature which highlight the effects and importance of shear flow in biological systems.
Adobe PDF, 117 KBytes, posted on Wednesday, June 10, 2009 at 9:14 AM
BioRheology 2008 Poster
Covers use of BioFlux system for cancer (colon carcinoma) cell adhesion applications.
Adobe PDF, 1.2 MBytes, posted on Tuesday, January 20, 2009 at 4:15 PM
Experimental Biology 2008 Poster
Covers use of BioFlux system for rolling adhesion and firm cell adhesion.
Adobe PDF, 910 KBytes, posted on Tuesday, January 20, 2009 at 4:15 PM
Lab Automation 2009 Poster
Covers use of BioFlux system for cell adhesion applications.
Adobe PDF, 943 KBytes, posted on Tuesday, January 20, 2009 at 3:24 PM
CHI Cell Based Assays for HTS 2008 Presentation
PowerPoint presentation covering use of BioFlux system for cell-based assays under shear flow.
Adobe PDF, 947 KBytes, posted on Tuesday, January 20, 2009 at 3:24 PM
CHI High Content Analysis 2009 Poster
Covers use of BioFlux system for cell adhesion and high content analysis assays using the CellCiphr toxicology kit.
Adobe PDF, 2.6 MBytes, posted on Tuesday, January 20, 2009 at 3:24 PM
BioFilms III 2008 Poster
Covers use of BioFlux system for growing and analyzing biofilms under shear flow.
Adobe PDF, 551 KBytes, posted on Tuesday, January 20, 2009 at 3:24 PM
American Society Matrix Biology 2008 Poster
Covers use of BioFlux system for cell adhesion, transmigration and wound healing.
Adobe PDF, 1.2 MBytes, posted on Tuesday, January 20, 2009 at 3:24 PM
American Society of Cell Biology 2008 Poster
Covers use of BioFlux system for cell adhesion, transmigration and wound healing.
Adobe PDF, 1.2 MBytes, posted on Tuesday, January 20, 2009 at 3:24 PM
Live Cell Imaging Advances (Drug Discovery & Development)
A review of current approaches to live cell imaging featured in Drug Discovery & Development (Feb 2008).
Adobe PDF, 57 KBytes, posted on Wednesday, December 03, 2008 at 10:19 AM
High Throughput Live Cell Imaging Assays (Gen Engineering News))
An overview article describing live cell assays for microbiology and cellular adhesion using the BioFlux 200. Presents an application overview and outlines some of the key benefits to running these assays using Well Plate Microfluidics.
Adobe PDF, 55 KBytes, posted on Tuesday, November 25, 2008 at 9:33 AM
Application Notes - Cell Biology (12 items)
Cellular Migration and Invasion
Application note covering BioFlux's unique ability to create microenvironmental regions using parallel flow, and utilize real-time imaging for kinetic observation.
Adobe PDF, 733 KBytes, posted on Tuesday, June 08, 2010 at 3:52 PM
Angiogenesis
Cancer cell invasion assay with real time imaging.
Adobe PDF, 583 KBytes, posted on Thursday, March 25, 2010 at 4:28 PM
Neurite Outgrowth
This application note describes a neurite outgrowth assay using the BioFlux system. Illustrates how the fluid addition steps can be done utilizing the rapid fluid exchange capabilties, without harming the neurite monolayer.
Adobe PDF, 2.4 MBytes, posted on Monday, March 16, 2009 at 1:17 PM
Stem Cell Differentiation
This application note describes use of the BioFlux System for running stem cell differentiation experiments. Highlights an example which depicts mesenchymal stem cells differentiated into endothelial cells utilizing shear stress.
Adobe PDF, 2.9 MBytes, posted on Monday, February 23, 2009 at 2:54 PM
Wound Healing
Adobe PDF, 1.1 MBytes, posted on Saturday, November 29, 2008 at 11:29 PM
Transmigration
Adobe PDF, 711 KBytes, posted on Saturday, November 29, 2008 at 11:29 PM
Stem Cells
Adobe PDF, 1.7 MBytes, posted on Saturday, November 29, 2008 at 11:29 PM
Rolling Adhesion
Adobe PDF, 2.3 MBytes, posted on Saturday, November 29, 2008 at 11:29 PM
Platelet Adhesion
Adobe PDF, 432 KBytes, posted on Saturday, November 29, 2008 at 11:29 PM
High Throughput Cell Adhesion
Adobe PDF, 1.4 MBytes, posted on Saturday, November 29, 2008 at 11:29 PM
Endothelial Cell Adhesion
Adobe PDF, 262 KBytes, posted on Saturday, November 29, 2008 at 11:20 PM
Cellular Adhesion Inhibition
Adobe PDF, 235 KBytes, posted on Saturday, November 29, 2008 at 11:20 PM
Application Notes - Microbiology (5 items)
High Content Analysis for Biofilms
Adobe PDF, 1.6 MBytes, posted on Saturday, November 29, 2008 at 11:47 PM
Anaerobic Biofilms

Adobe PDF, 1.3 MBytes, posted on Saturday, November 29, 2008 at 11:42 PM
Host Pathogen Interactions
Adobe PDF, 1.9 MBytes, posted on Saturday, November 29, 2008 at 11:29 PM
Biofilm Growth
Adobe PDF, 316 KBytes, posted on Saturday, November 29, 2008 at 11:20 PM
Biofilms Compound Screening
Adobe PDF, 506 KBytes, posted on Saturday, November 29, 2008 at 11:20 PM
Technical Notes (12 items)
BioFlux PC Requirements
Provides the minimum and recommended computer requirements to run BioFlux software.
Adobe PDF, 222 KBytes, posted on Friday, October 30, 2009 at 9:46 AM
Whole Blood Assays
Describes best practices for running whole blood assays on the BioFlux System. Includes cleaning procedures.
Adobe PDF, 4.2 MBytes, posted on Friday, May 01, 2009 at 11:33 AM
High Content Screening Kits
This technical note describes the use of commercially-available fluorescence based staining kits for high content analysis. Highlights an example of using toxicology markers for epithelial cells under shear flow.
Adobe PDF, 3.4 MBytes, posted on Monday, March 16, 2009 at 1:26 PM
Viscosity in the BioFlux System
Provides a general overview of fluid viscosity and how it relates to BioFlux experiments. Includes suggestions for how to estimate and measure viscosity of a variety of biological fluids, including whole blood.
Adobe PDF, 1.2 MBytes, posted on Thursday, January 29, 2009 at 9:28 AM
Imaging Capabilities
An overview of BioFlux imaging properties and description of common imaging modalities including brightfield, phase contrast, fluorescence and confocal microscopy. Includes sample images.
Adobe PDF, 4.3 MBytes, posted on Monday, December 08, 2008 at 7:59 AM
Preconditioning Endothelial Cell Monolayers
Adobe PDF, 1.8 MBytes, posted on Saturday, November 29, 2008 at 11:42 PM
Growing Cellular Monolayers
Adobe PDF, 1.8 MBytes, posted on Saturday, November 29, 2008 at 11:42 PM
Growing Airway Epithelial Cell Monolayers
Adobe PDF, 1.3 MBytes, posted on Saturday, November 29, 2008 at 11:42 PM
Reproducibility of Cellular Adhesion Assays
Adobe PDF, 765 KBytes, posted on Saturday, November 29, 2008 at 11:42 PM
Protocols (4 items)
Platelet Protocol - Physiological Shear
Adobe PDF, 2.6 MBytes, posted on Friday, March 26, 2010 at 9:16 AM
Platelet Protocol - High Shear
Adobe PDF, 3.7 MBytes, posted on Friday, March 26, 2010 at 9:15 AM
Platelet Inhibition Protocol
Adobe PDF, 2.5 MBytes, posted on Friday, March 26, 2010 at 9:13 AM
Micropatterning Matrigel in the BioFlux System
Protocol for the angiogenesis and cell invasion assay.
Adobe PDF, 64 KBytes, posted on Friday, March 26, 2010 at 9:12 AM
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