BioFlux
Live cell analysis under shear flow
BioFlux provides a fully integrated solution for running biologically relevant cellular assays under shear flow. The system utilizes Fluxion's Well Plate Microfluidics™ (WPM) to provide high content results from a convenient well-plate format. Precise control over shear flow enables a wide variety of cellular and microbiology applications which call for vascular emulation, mechanical stress, compound/buffer exchange and high content analysis.
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Add biological relevance to your static well assays
BioFlux offers a unique solution to bridge the gap between in vitro and in vivo assays by combining the ease of use and throughput of a well plate with the data quality of a shear flow assay. BioFlux gives you the best of all worlds.
Simplifying complex functional assays with Well Plate Microfluidics (WPM) technology
The BioFlux system integrates complex procedural assays into a simple to use, scalable and reliable system. It enables shear stress dependant assays such as adhesion, biofilms, transmigration, wound healing, stem cells, platelet adhesion or any assay which can benefit from the use of shear flow. BioFlux flow control also provides the ability to do real-time compound and buffer exchanges.
Reduce experimental time frames from months to days
The BioFlux well-plate design enables you to run up to 96 assays at a time. Having this kind of throughput allows all test and control experiments to be run at the same time, under the same conditions. This greatly enhances data reliability and reduces experimental time from months to days. This translates to faster results and quicker time to publication.
Precise control over shear flow
The electro-pneumatic pumping technology employed by the BioFlux controller allows an identical shear rate to be applied across all the channels of the BioFlux Plate. Shear flows up to 200 dynes/cm2 enable a wide range of reproducible assays.
Simplified automation
BioFlux can be adapted to any existing inverted microscope in your lab. Automation protocols using standard microscopy accessories will put you first when it comes to productivity and publications.
One system...many applications
BioFlux enables a wide variety of cell-based assays in the fields of immunology, vascular biology, microbiology, cancer research, stem cells, and more. Many of these applications benefit from the ability to create a physiologically-relevant shear flow profile, such as platelet adhesion, cell adhesion, rolling velocity, transmigration and stem cell differentiation. Other applications can benefit from the ability to introduce compounds in a time-resolved and well-controlled manner, such as wound healing, pharmacology and neurite-outgrowth assays. Feel free to browse our extensive library of Application and Technical Notes, and contact us to discuss your applications with us.
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BioFlux System Configurations
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BioFlux 200
BioFlux 200 provides everything you need to be up and running. It integrates with any inverted microscope and offers complete control over shear-flow assays.
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 | System ships with: - BioFlux Controller
- BioFlux 200 Well Plate Interface (24-well or 48-well)
- BioFlux 200 Software (experimental control, image acquisition/analysis)
- Heating plate
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BioFlux 1000
BioFlux 1000 offers a fully-integrated solution for automated, high throughput shear flow assays. High performance microscopy components are seamlessly integrated with BioFlux controls to offer the ultimate in speed, precision and convenience. |
.jpg) | System ships with: - BioFlux Controller
- BioFlux 1000 Well Plate Interface (24-well or 48-well)
- BioFlux Montage software (experimental control, hardware control, image acquisition/analysis)
- Inverted microscope and objectives
- CCD camera
- Customized automated stage (linear encoded, 0.1µm resolution)
- Integrated plate loading tray for BioFlux Plates
- Auto-focus drive
- PC pre-loaded with Montage software
- Accessories:
- Stage heater or incubation chamber
- Epi-fluorescence module
- Vibration isolation table
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