Modeling of Catheter-Associated Infection and Evaluating Antimicrobial Drug Efficacy Using Novel Microfluidic System
Speaker: Dr. Claudia Vuotto, PhD, Team Leader at Microbial Biofilm Laboratory,...
At Fluxion, we’re passionate about delivering cell-based and cell-free solutions that facilitate the transformation of research discoveries into new ways to diagnose and treat patients. By characterizing molecular and cellular mechanisms of disease, Fluxion’s platforms help bridge the translational medicine gap, enabling rapid advances in disease research, drug discovery, and the development of diagnostic tests.
Many physiological processes take place under flow conditions: blood flowing through the vasculature; cancer cells circulating throughout the body; plaque forming on teeth under the presence of saliva flow. It is now well established that physiological flow has a profound impact on many biological studies, yet much research is still conducted in vitro without the presence of flow. BioFlux from Fluxion Biosciences gives you the ability to introduce flow to your research and drug discovery experiments, effectively emulating in vivo conditions and revealing the true biology.
antimicrobial screening, biofilm formation, & host-pathogen interactions
antimicrobial screening, biofilm formation, & host-pathogen interactions
More Informationthrombosis, platelet activity, & atherosclerosis models
immune cell analysis, wound healing, & rheumatology
immunotherapy research, tumor microenvironment, cancer cell biology
Live cell assays are often performed in well plates to test multiple conditions and compounds in parallel. But many biological questions require more than simply adding cells into a dish. The BioFlux system provides the ability to emulate physiological shear flow in an in vitro model, while still maintaining a convenient well plate format. This opens up a multitude of experiments which could never be done in static well plates.
Read more about microfluidics-based flow technology.
BioFlux systems come in different configurations to match laboratory and project needs. download the product brochures and the selection guide to research your ideal system.
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Looking for a simple microfluidic solution for your current microscope? The BioFlux One can run up to 24 simultaneous flow cell experiments and is ideal for platelet aggregation, leukocyte adhesion, and biofilm analysis. It works with your existing inverted microscope and is compatible with fluorescence, brightfield, phase and confocal imaging.
Looking to add functionality to your existing microscopy setup? The BioFlux 200 expands on BioFlux One by enabling up to 24 temperature-controlled flow cell assays in parallel. The dual flow control capability enables more complicated 2-phase flow assays. It is also compatible with the BioFlux Quattro for up to 96 parallel flow assays.
Looking for a simple, fully integrated solution? The BioFlux DCIS integrates the BioFlux controller with a digital microscope, fluorescence, and two cameras. The easy-to-use live cell imaging system been designed with advanced capabilities to simplify demanding cell-based imaging applications with convenience and flexibility.
Looking for the ultimate solution for imaging flexibility and capability? The BioFlux 1000z offers nearly unlimited flexibility with respect to microscope options, software analysis, and image capture. It provides a high content screening platform for running physiologically-relevant shear flow assays.
Most Cost-Effective
Flow Assays
Fits in Hood
Temperature control (Optional)
48 well plate format
Adapts to existing microscope
BioFlux analysis software (included)
Montage Software (Optional)
24 Flow assays
Most Versatile
Flow Assays (+ Quattro)
Fits in Hood
Temperature control (standard)
48/24 Well plate format
Adapts to existing microscope
BioFlux analysis software (included)
Montage software (optional)
24 Flow assays standard
96 Flow assays with Quattro
Most Integrated
Flow Assays (+ Quattro)
Fits in Hood
Temperature control (standard)
48/24/6 Well plate format
Standard configuration microscope
BioFlux analysis software (included)
Montage offline software (included)
24 Flow assays standard
96 Flow assays with Quattro
Autofocus
Monochrome & color cameras
Epifluorescence
DAPI, GFP, RFP filter cubes
Motorized stage
Onstage incubator (optional)
4 Fluorescence channels
10X & 20X included objectives, 5 positions
Endpoint & live cell imaging
Automated plate scanning
Most Custumizable
Flow Assays (+ Quattro)
-
Temperature control (standard)
48/24/6 Well plate format
Fully customizable microscope
Montage integrated advanced control
Montage software (included)
24 Flow assays standard
96 Flow assays with Quattro
Autofocus
User defined cameras
Epifluorescence
User selected filter cubes
Motorized stage
Onstage incubator (optional enclosure)
6 Fluorescence channels
10X & 20X included objectives, 6 positions
Endpoint & live cell imaging
Automated plate scanning
BioFlux microfluidic plates are available in a range of formats tailored to specific cell assay requirements.
Visit our library of application notes, webinars, live demos, posters and publications featuring BioFlux technology.
For additional support, customers can access our support site for operation technical guides, cell culture optimizations, software updates, pre-recorded training, and troubleshooting guides.
Speaker: Dr. Claudia Vuotto, PhD, Team Leader at Microbial Biofilm Laboratory,...
Speakers: Jeff Jensen, CEO, Fluxion Biosciences
About This Presentation
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Speaker:Dr. Giordano Pula, PhD, Group Leader for Haemostasis and Thrombosis,...