Immune Cell Analysis, Cell Adhesion/Rolling, and Transmigration
Proper immune function depends on the interconnected relationships of many diverse cell types. When improperly functioning, these cell-cell interactions can lead to allergy, asthma, autoimmune and infectious disease. Immune surveillance in large part occurs within the vasculature in the presence of constant flow, where cell-cell and cell-ligand interactions are influenced by in situ forces.
BioFlux serves as a multiplexed "artery on a chip" system to model the immune system's in vivo environment, uncover novel immune biology, and develop new treatments.