Pharmacological Characterization of a Primary Nicotinic Receptor from the Neuromuscular Junction
Speakers: Andrew Cook, Senior Study Director, Eurofins Discovery Services
Abstract:
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IonFlux Application Areas
Due to its unique liquid exchange system, IonFlux is the ideal platform for ligand binding, allosteric modulation, multiple agonists, and voltage- and temperature-sensitive assays. It is used in laboratories and research centers worldwide for various voltage gated and ligand gated ion channels assays.
From safety pharmacology to sleep disorders, ion channel research and screening assays are simplified with IonFlux technology. Read more about ion channel applications with IonFlux.
IonFlux provides the highest degree of control over fluidics for specialized ion channel assays. With its unique microfluidic plates, IonFlux is the only system where all cell recordings and liquid exchange are performed within the plate proper. Without the hindrance of liquid handlers, the system advances high throughput ion channel experiments by providing unique attributes that permit specialized assays, impossible or impractical using other asynchronous systems.
IonFlux from Fluxion Biosciences comes in different versions catering to different laboratories and project needs. download the product brochures and the selection guide to research the best system for your needs.
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IonFlux Mercury 16
PATCH CLAMP AUTOMATION AT THE PRICE OF MANUAL
IonFlux Mercury 16 represents the next generation in the automated patch clamp system. With features such as 16 parallel recordings using 16 independent amplifiers, remote and touch screen experiment execution, highly extended recording times, exceptionally fast fluid exchange system, standardized temperature control, and optional current clamp. IonFlux Mercury is the most compact yet full featured stand-alone high throughput automated patch clamp instrument on the market.
IonFlux Mercury HT
HIGH THROUGHPUT AUTOMATION FOR FLOW DEPENDENT ASSAYS
The IonFlux Mercury HT takes all the technology of the IonFlux Mercury 16 and multiplies the throughput by 4. With 64 amplifiers, continuous flow and extremely flexible liquid exchange, the IonFlux Mercury HT can sometimes be the only means to achieve higher throughput with extremely complicated flow-dependent ion channel assays.
IonFlux Mercury ULTRA
THE HIGHEST THROUGHPUT CONTINUOUS FLOW APC SYSTEM ON THE MARKET
IonFlux Mercury Ultra is the latest iteration of the industry-leading IonFlux platform, with enhancements in every aspect of the technology. With 256 independent amplifiers capable of non-stop recordings, and an uninterrupted sweep length of up to 300 seconds, IonFlux Mercury Ultra extends the IonFlux system’s industry-leading capabilities in compound delivery, rapid solution exchange, and assay flexibility. Now, the most complicated ligand-gated and demanding voltage-gated assays can run in parallel, decreasing experiment time and accelerating completion of projects.
Its all in the consumables
IonFlux utilizes in-plate solution transfer that is made possible by SBS standard plates with intricate microfluidics
Automate IonFlux Assays
Mercury Automate is a new Liquid Handler specially configured for IonFlux assays. Included free with IonFlux Mercury HT and ULTRA
